15-keto-Prostaglandin E2
Product Specifications
CAS Number
26441-05-4
Target
Prostaglandin Receptor|||STAT|||Endogenous Metabolite|||PPAR
Related Pathways
Stem Cells|||JAK/STAT signaling|||Metabolism|||Immunology/Inflammation|||DNA Damage/DNA Repair|||GPCR/G Protein
Bioactivity
15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast cancer cell growth and progression. Additionally, it binds and stabilizes the EP2 and EP4 receptors, activates PPAR-?, and promotes fungal growth [1] [2] [3].
Smiles
CCCCCC(=O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
Molecular Formula
C20H30O5
Molecular Weight
350.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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