NSC260594
Product Specifications
CAS Number
906718-66-9
Target
Others, Apoptosis, Bcl-2 Family, HIV Protease, Wnt/beta-catenin
Related Pathways
Apoptosis, Proteases/Proteasome, Others, Microbiology/Virology, Cytoskeletal Signaling, Stem Cells
Bioactivity
NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-regulation of Wnt signaling proteins. Additionally, it can identify the G9-G10-A11-G12 RNA tetraloop of HIV, thereby obstructing the attachment of the Gag protein to the 5'-UTR. This compound demonstrates the potential to impede tumor proliferation and is utilized in the study of Triple-negative breast cancers (TNBCs) [1].
Smiles
Cn1cc\c(cc1)=N\c1ccc(NC(=O)c2ccc(cc2)N=c2ccn(C)c3ccc(cc23)[N+]([O-])=O)cc1
Molecular Formula
C29H24N6O3
Molecular Weight
504.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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