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NSC260594

Product Specifications

CAS Number

906718-66-9

Target

Others, Apoptosis, Bcl-2 Family, HIV Protease, Wnt/beta-catenin

Related Pathways

Apoptosis, Proteases/Proteasome, Others, Microbiology/Virology, Cytoskeletal Signaling, Stem Cells

Bioactivity

NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-regulation of Wnt signaling proteins. Additionally, it can identify the G9-G10-A11-G12 RNA tetraloop of HIV, thereby obstructing the attachment of the Gag protein to the 5'-UTR. This compound demonstrates the potential to impede tumor proliferation and is utilized in the study of Triple-negative breast cancers (TNBCs) [1].

Smiles

Cn1cc\c(cc1)=N\c1ccc(NC(=O)c2ccc(cc2)N=c2ccn(C)c3ccc(cc23)[N+]([O-])=O)cc1

Molecular Formula

C29H24N6O3

Molecular Weight

504.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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