EGFR-IN-85
Product Specifications
CAS Number
1956378-29-2
Target
EGFR
Related Pathways
JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
EGFR-IN-85 (Compound 1), an EGFR inhibitor, exhibits potent activity with an IC50 of 0.19 μM against EGFRvIII phosphorylation and can suppress intratumoral EGFR signaling. It is utilized in Glioblastoma (GBM) research [1].
Smiles
N(C=1N=C(N2C=3C(C=C2)=CC=CN3)C=CN1)C4=C(OC)C=C(N(CCN(C)C)C)C(NC(C=C)=O)=C4
Molecular Formula
C26H30N8O2
Molecular Weight
486.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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