PB118
Product Specifications
Target
Others, HDAC
Related Pathways
Others, Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
PB118 has the capacity to effectively clear Aβ deposits by augmenting phagocytosis, enhance the tubulin/microtubule network through increased acetyl α-tubulin levels, modulate various inflammation-associated cytokines and chemokines, and notably diminish phospho-tau (p-tau) levels linked to Alzheimer's disease (AD) . The IC50 of PB118 for HDAC6 is 5.6 nM.
Smiles
O=C(NO)C1=CC(F)=C(CN2CCCCC3=CC=CC=C32)C=C1
Molecular Formula
C18H19FN2O2
Molecular Weight
314.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
38518116 3x 1.0 µg
Rarres2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
Sign In for Pricing
View Details 
TL300567V 500 µL Each
VN1R2 Human shRNA Lentiviral Particle (Locus ID 317701)
Sign In for Pricing
View Details 