Glucosylsphingosine
Product Specifications
CAS Number
52050-17-6
Target
MTOR|||Glucokinase|||Drug Metabolite|||glycosidase
Related Pathways
PI3K/Akt/mTOR signaling|||Metabolism
Bioactivity
Glucosylsphingosine (Lyso-Gb1) is a naturally occurring glycosyl ceramide, a metabolite of GBA (acid ?-glucosidase), involved in cellular recognition, signaling, and intercellular interactions.Glucopsychosine accumulates in certain neurodegenerative diseases (e.g., Gaucher disease), disrupts lysosomal function through activation of mammalian target of rapamycin complex 1 (mTORC1), and is a noncompetitive inhibitor of glucocerebrosidase.
Smiles
O(C[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)N)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Molecular Formula
C24H47NO7
Molecular Weight
461.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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