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Pyridinium bisretinoid A2E TFA

Product Specifications

CAS Number

1821308-73-9

Target

Autophagy|||Apoptosis|||Reactive Oxygen Species|||ROS

Related Pathways

NF-?B|||Immunology/Inflammation|||Apoptosis|||Metabolism|||Autophagy

Bioactivity

Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2].

Smiles

C(C([O-])=O)(F)(F)F.C(CO)[N+]=1C(/C=C(/C=C/C=C(/C=C/C=2C(C)(C)CCCC2C)\C)\C)=CC(/C=C/C=C(/C=C/C=3C(C)(C)CCCC3C)\C)=CC1

Molecular Formula

C44H58F3NO3

Molecular Weight

705.93

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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