Pyridinium bisretinoid A2E TFA
Product Specifications
CAS Number
1821308-73-9
Target
Autophagy|||Apoptosis|||Reactive Oxygen Species|||ROS
Related Pathways
NF-?B|||Immunology/Inflammation|||Apoptosis|||Metabolism|||Autophagy
Bioactivity
Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2].
Smiles
C(C([O-])=O)(F)(F)F.C(CO)[N+]=1C(/C=C(/C=C/C=C(/C=C/C=2C(C)(C)CCCC2C)\C)\C)=CC(/C=C/C=C(/C=C/C=3C(C)(C)CCCC3C)\C)=CC1
Molecular Formula
C44H58F3NO3
Molecular Weight
705.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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