IV-255
Product Specifications
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
IV-255 is a selective small molecule inhibitor of the BRG1 bromodomain, which heightens DNA damage when administered with Temozolomide and Bleomycin, curtails the invasiveness of GBM cells, and augments both Temozolomide-induced cell death and Temozolomide's apoptosis-inducing activity [1].
Molecular Formula
C19H19F2N3O2
Molecular Weight
359.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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