PU-48
Product Specifications
CAS Number
335394-78-0
Target
Others, Urea Transporter
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
PU-48 is a potent inhibitor of urea transporters A (UT-A) with an IC50 value of 0.32 μM, exhibiting a significant diuretic effect in mouse models without notable cytotoxicity. This compound has the potential for further development as a diuretic [1].
Smiles
O=C(OC)C=1SC=2N=C3C=CC(OC)=CC3=CC2C1N
Molecular Formula
C14H12N2O3S
Molecular Weight
288.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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