S07-1066
Product Specifications
CAS Number
876625-29-5
Target
Dehydrogenase, Others
Related Pathways
Others, Metabolism
Bioactivity
S07-1066, an aldo-keto reductase 1C3 (AKR1C3) inhibitor, enhances doxorubicin (DOX) cytotoxicity by selectively inhibiting AKR1C3-mediated reduction of DOX and reversing DOX resistance in cells with elevated AKR1C3 expression [1].
Smiles
O=C(O)C1(C=2C=CC(=C(F)C2)C3=CC(Cl)=CC(Cl)=C3)CC1
Molecular Formula
C16H11Cl2FO2
Molecular Weight
325.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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