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S07-1066

Product Specifications

CAS Number

876625-29-5

Target

Dehydrogenase|||Others

Related Pathways

Others|||Metabolism

Bioactivity

S07-1066, an aldo-keto reductase 1C3 (AKR1C3) inhibitor, enhances doxorubicin (DOX) cytotoxicity by selectively inhibiting AKR1C3-mediated reduction of DOX and reversing DOX resistance in cells with elevated AKR1C3 expression [1].

Smiles

O=C(O)C1(C=2C=CC(=C(F)C2)C3=CC(Cl)=CC(Cl)=C3)CC1

Molecular Formula

C16H11Cl2FO2

Molecular Weight

325.16

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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