JAK-IN-26
Product Specifications
CAS Number
2417134-93-9
Target
JAK
Related Pathways
Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis
Bioactivity
JAK-IN-26 (compound 2) is an orally active Janus kinase (JAK) inhibitor with favorable pharmacokinetic properties, demonstrating potency in suppressing IFN-α2B-induced STAT3 phosphorylation in Jurkat cells, with an IC50 value of 17.2 nM [1].
Smiles
O=C(NC1=NC=C(C(=O)CC)C(=C1)NC2=CC=CC(C=3N=CN(N3)C)=C2OC)C4CC4
Molecular Formula
C22H24N6O3
Molecular Weight
420.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV752128 1.0 µg DNA
TRNAG36 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details 
TA805952AM 100 µL
CDKL1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5B10]
Sign In for Pricing
View Details