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JAK-IN-26

Product Specifications

CAS Number

2417134-93-9

Target

JAK

Related Pathways

Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis

Bioactivity

JAK-IN-26 (compound 2) is an orally active Janus kinase (JAK) inhibitor with favorable pharmacokinetic properties, demonstrating potency in suppressing IFN-α2B-induced STAT3 phosphorylation in Jurkat cells, with an IC50 value of 17.2 nM [1].

Smiles

O=C(NC1=NC=C(C(=O)CC)C(=C1)NC2=CC=CC(C=3N=CN(N3)C)=C2OC)C4CC4

Molecular Formula

C22H24N6O3

Molecular Weight

420.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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