JAK-IN-26
Product Specifications
CAS Number
2417134-93-9
Target
JAK
Related Pathways
Tyrosine Kinase/Adaptors|||Stem Cells|||JAK/STAT signaling|||Chromatin/Epigenetic|||Angiogenesis
Bioactivity
JAK-IN-26 (compound 2) is an orally active Janus kinase (JAK) inhibitor with favorable pharmacokinetic properties, demonstrating potency in suppressing IFN-?2B-induced STAT3 phosphorylation in Jurkat cells, with an IC50 value of 17.2 nM [1].
Smiles
O=C(NC1=NC=C(C(=O)CC)C(=C1)NC2=CC=CC(C=3N=CN(N3)C)=C2OC)C4CC4
Molecular Formula
C22H24N6O3
Molecular Weight
420.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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