NLRP3-IN-17
Product Specifications
CAS Number
2254432-75-0
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome with an IC50 of 7 nM, effectively inhibiting NLRP3-dependent IL-1β secretion in mice, making it valuable for chronic inflammatory disease research [1].
Smiles
N#CN=S(=O)(NC(=O)NC=1C2=C(C=C3C1CCC3)CCC2)C4=CC=C(C=C4)C
Molecular Formula
C21H22N4O2S
Molecular Weight
394.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C