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PARP-1-IN-3

Product Specifications

CAS Number

2976342-33-1

Target

PARP|||Caspase|||Apoptosis

Related Pathways

Chromatin/Epigenetic|||Proteases/Proteasome|||DNA Damage/DNA Repair|||Apoptosis

Purity

0.9986

Bioactivity

PARP-1-IN-3 is a potent PARP-1 inhibitor that inhibits PARP-1 and PARP-2 with IC50 values of 0.25 nM and 2.34 nM, respectively.PARP-1-IN-3 has potential anti-inflammatory activity, induces apoptosis, and arrests the cell cycle in the G2/M phase.PARP-1-IN-3 may be useful for the study of cancer-related diseases. cancer-related diseases.

Smiles

O=C(N)C=1C=CC=CC1OCC=2C=CC=C(C2)NC(=O)C3=CC=C(Br)C=C3

Molecular Formula

C21H17BrN2O3

Molecular Weight

425.28

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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