PARP-1-IN-3
Product Specifications
CAS Number
2976342-33-1
Target
PARP|||Caspase|||Apoptosis
Related Pathways
Chromatin/Epigenetic|||Proteases/Proteasome|||DNA Damage/DNA Repair|||Apoptosis
Purity
0.9986
Bioactivity
PARP-1-IN-3 is a potent PARP-1 inhibitor that inhibits PARP-1 and PARP-2 with IC50 values of 0.25 nM and 2.34 nM, respectively.PARP-1-IN-3 has potential anti-inflammatory activity, induces apoptosis, and arrests the cell cycle in the G2/M phase.PARP-1-IN-3 may be useful for the study of cancer-related diseases. cancer-related diseases.
Smiles
O=C(N)C=1C=CC=CC1OCC=2C=CC=C(C2)NC(=O)C3=CC=C(Br)C=C3
Molecular Formula
C21H17BrN2O3
Molecular Weight
425.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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