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CS640

Product Specifications

CAS Number

2388506-83-8

Target

Others

Related Pathways

Others

Bioactivity

CS640 is a selective calmodulin-dependent kinase inhibitor, targeting multiple isoforms, namely CaMK1D, CaMK1B, CaMK1A, CaMK1G, PIP5K1C, MEK5, RIPK4, and MLK3, with respective IC50 values of 0.08, 0.03, 0.001, 0.001, 11.2, 0.025, 5.69, and 2.75 μM. Additionally, CS640 exhibits inhibitory properties toward CYP450 enzymes 2C9 and 2C19 with IC50 values of 6 and 10 μM, correspondingly [1].

Smiles

N(C=1C(C(N)=O)=CN=C(N1)N2C[C@@H](N)CCC2)C=3C=C(C(C)C)N=C(C(C)C)C3

Molecular Formula

C21H31N7O

Molecular Weight

397.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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