Bleximenib oxalate
Product Specifications
CAS Number
2866179-95-3
Target
Epigenetic Reader Domain, Histone Methyltransferase, Apoptosis, FLT
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Apoptosis
Bioactivity
Bleximenib oxalate (Menin-MLL inhibitor 24 oxalate) is a selective and highly efficient menin-MLL inhibitor. It shows antiproliferative activity in acute lymphoblastic leukemia (ALL) cell lines and inhibits the binding of the menin-KMT2A complex to chromatin at the target gene promoter.
Smiles
C(C(O)=O)(O)=O.[C@@H](CCCN(CCOC)C)(C(C)C)N1CC2(CN(CC2)C=3C(OC4=C(C(N(C(C)C)CC)=O)C=C(F)C=C4)=NN=CN3)C1
Molecular Formula
C34H52FN7O7
Molecular Weight
689.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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