SIC5-6
Product Specifications
CAS Number
2410846-16-9
Target
Others
Related Pathways
Others
Bioactivity
SIC5-6 is a potent inhibitor of Separase, a substantial cysteine protease implicated in critical cellular processes such as chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement and duplication, as well as spindle stabilization and elongation. Given its overexpression in many solid cancers, Separase presents an attractive target for chemotherapy [1].
Smiles
O=S(=O)(C1=CC=C(I)C=C1)N2CCC(C3=CNC=4C=CC=CC43)(C5=CNC=6C=CC=CC65)CC2
Molecular Formula
C27H24IN3O2S
Molecular Weight
581.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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