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PVZB1194

Product Specifications

CAS Number

1141768-04-8

Target

Kinesin

Related Pathways

Cytoskeletal Signaling

Bioactivity

PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inhibiting Eg5 ATPase activity. It binds to the α4/α6 allosteric pocket and demonstrates ATP-competitive activity [1].

Smiles

O=S(=O)(N)C1=CC=C(C=C1)C=2C=CC(=C(F)C2)C(F)(F)F

Molecular Formula

C13H9F4NO2S

Molecular Weight

319.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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