PVZB1194
Product Specifications
CAS Number
1141768-04-8
Target
Kinesin
Related Pathways
Cytoskeletal Signaling
Bioactivity
PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inhibiting Eg5 ATPase activity. It binds to the ?4/?6 allosteric pocket and demonstrates ATP-competitive activity [1].
Smiles
O=S(=O)(N)C1=CC=C(C=C1)C=2C=CC(=C(F)C2)C(F)(F)F
Molecular Formula
C13H9F4NO2S
Molecular Weight
319.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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