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Z-L (D-Val) G-CHN2

Product Specifications

Target

SARS-CoV, Cysteine Protease, HSV

Related Pathways

Proteases/Proteasome, Microbiology/Virology

Bioactivity

Z-L (D-Val) G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase. This tripeptide derivative emulates a segment of the human cysteine proteinase-binding center and demonstrates selective antiviral activity, inhibiting herpes simplex virus (HSV) yet exhibiting negligible impact on poliovirus replication. Notably, Z-LVG-CHN2 effectively impedes SARS-CoV-2 replication with an EC50 value of 190 nM by targeting the SARS-CoV-2 3CL protease [3].

Molecular Formula

C22H31N5O5

Molecular Weight

445.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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