Demethyleneberberine chloride
Product Specifications
CAS Number
16705-03-6
Target
AMPK, NF-κB
Related Pathways
NF-κB, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic
Bioactivity
Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by blocking the NF-κB pathway and modulating the equilibrium of Th cells. It is also recognized as an AMPK activator for investigating non-alcoholic fatty liver disease (NAFLD) [1] [2] [3].
Smiles
[Cl-].OC=1C=C2C=3C=C4C=CC(OC)=C(OC)C4=C[N+]3CCC2=CC1O
Molecular Formula
C19H18ClNO4
Molecular Weight
359.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E28PP1166 100 µL
Cyclin E1 (phospho Thr77) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details 
orb2905234-01 20 µg
Recombinant Rat C-C chemokine receptor type 5 (Ccr5)
Sign In for Pricing
View Details orb2905234-02 100 µg
Recombinant Rat C-C chemokine receptor type 5 (Ccr5)
Sign In for Pricing
View Details 
MBS6431840-01 0.1 mL
PLA2G2A (Phospholipase A2, Membrane Associated, Phospholipase A2, Group IIA, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2) (MaxLight 750)
Sign In for Pricing
View Details MBS6431840-02 5x 0.1 mL
PLA2G2A (Phospholipase A2, Membrane Associated, Phospholipase A2, Group IIA, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2) (MaxLight 750)
Sign In for Pricing
View Details