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Demethyleneberberine chloride

Product Specifications

CAS Number

16705-03-6

Target

AMPK, NF-κB

Related Pathways

NF-κB, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic

Bioactivity

Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by blocking the NF-κB pathway and modulating the equilibrium of Th cells. It is also recognized as an AMPK activator for investigating non-alcoholic fatty liver disease (NAFLD) [1] [2] [3].

Smiles

[Cl-].OC=1C=C2C=3C=C4C=CC(OC)=C(OC)C4=C[N+]3CCC2=CC1O

Molecular Formula

C19H18ClNO4

Molecular Weight

359.8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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