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ProTx II TFA

Product Specifications

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over other sodium channel subtypes. It decreases channel conductance, shifts activation towards more positive potentials, and inhibits action potential propagation in nociceptors [1] [2].

Molecular Formula

C168H250N46O41S8.xC2HF3O2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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