ProTx II TFA
Product Specifications
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over other sodium channel subtypes. It decreases channel conductance, shifts activation towards more positive potentials, and inhibits action potential propagation in nociceptors [1] [2].
Molecular Formula
C168H250N46O41S8.xC2HF3O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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