HMGB1-IN-1
Product Specifications
Target
Others|||NOD-like Receptor (NLR) |||Interleukin|||TNF
Related Pathways
Others|||Apoptosis|||Immunology/Inflammation
Bioactivity
HMGB1-IN-1 (compound 6) exhibits potent inhibition of NO production in RAW264.7 cells, with an IC50 of 15.9 ± 0.6 ?M, and effectively disrupts the HMGB1/NF-?B/NLRP3 signaling pathway, demonstrating promising anti-inflammatory and anti-sepsis properties, particularly in the context of renal injury [1].
Molecular Formula
C57H75N3O15
Molecular Weight
1042.22
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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