Necrocide 1
Product Specifications
CAS Number
1247028-61-0
Target
TRP/TRPV Channel, ROS, PERK, Others, Necroptosis
Related Pathways
Immunology/Inflammation, Membrane transporter/Ion channel, Others, Apoptosis
Bioactivity
Necrocide 1 is a potent inducer of cancer cell necrosis that is not inhibited by caspase blockers, anti-apoptotic BCL2 overexpression, or TNFα neutralization at nanomolar concentrations, and acts through the mitochondrial regulatory pathway.
Smiles
O=C1[C@](C=2C(N1)=C(C)C(OC)=CC2)(C3=CC=C(O)C=C3)C4CCCCCC4
Molecular Formula
C23H27NO3
Molecular Weight
365.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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