PAMP-12 (unmodified) acetate

Product Specifications

Target

Others, Adrenergic Receptor

Related Pathways

Neuroscience, GPCR/G Protein, Others

Purity

0.9897

Bioactivity

PAMP-12 (unmodified) acetate is an endogenous peptide and potent agonist of the MRGPRX2 (MrgX2) receptor with an EC50 ranging from 20 to 50 nM. PAMP-12 (unmodified) mediates hypotensive effects by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells, serving as a critical tool in the study of neuroimmune interactions and cardiovascular regulation.

Smiles

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