ATWLPPR Peptide
Product Specifications
CAS Number
272121-15-0
Target
VEGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
ATWLPPR Peptide is a biologically active peptide functioning as a specific antagonist to VEGFR2/KDR. It binds to VEGFR2 (KDR/flk), thereby completely inhibiting VEGF binding to KDR and blocking VEGF-induced angiogenesis in vivo. Moreover, it selectively inhibits human endothelial cell proliferation in vitro and effectively abolishes VEGF-induced angiogenesis in vivo.
Smiles
C([C@@H](C(N[C@H](C(=O)N1[C@H](C(=O)N2[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC2)CCC1)CC(C)C)=O)NC([C@@H](NC([C@H](C)N)=O)[C@@H](C)O)=O)C=3C=4C(NC3)=CC=CC4
Molecular Formula
C40H61N11O9
Molecular Weight
839.98
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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