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ATWLPPR Peptide

Product Specifications

CAS Number

272121-15-0

Target

VEGFR

Related Pathways

Tyrosine Kinase/Adaptors|||Angiogenesis

Bioactivity

ATWLPPR Peptide is a biologically active peptide functioning as a specific antagonist to VEGFR2/KDR. It binds to VEGFR2 (KDR/flk), thereby completely inhibiting VEGF binding to KDR and blocking VEGF-induced angiogenesis in vivo. Moreover, it selectively inhibits human endothelial cell proliferation in vitro and effectively abolishes VEGF-induced angiogenesis in vivo.

Smiles

C([C@@H](C(N[C@H](C(=O)N1[C@H](C(=O)N2[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC2)CCC1)CC(C)C)=O)NC([C@@H](NC([C@H](C)N)=O)[C@@H](C)O)=O)C=3C=4C(NC3)=CC=CC4

Molecular Formula

C40H61N11O9

Molecular Weight

839.98

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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