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Thalidomide-NH-C9-NH2 hydrochloride

Product Specifications

CAS Number

2305936-77-8

Target

Others, Ligand for E3 Ligase

Related Pathways

Others, PROTAC

Bioactivity

Thalidomide-NH-C9-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein. This compound can be conjugated to a protein-targeting ligand via a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs) [1].

Smiles

Cl.O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCCCCCCCN)C3C2=O)CC1

Molecular Formula

C22H31ClN4O4

Molecular Weight

450.96

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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