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PROTAC BCR-ABL Degrader-1

Product Specifications

Target

Bcr-Abl, PROTACs

Related Pathways

Tyrosine Kinase/Adaptors, PROTAC, Cytoskeletal Signaling, Angiogenesis

Bioactivity

PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, induces Bcr-Abl degradation via the ubiquitin-proteasome pathway and exhibits antiproliferative effects on K562 cells, indicating its potential in cancer research [1].

Molecular Formula

C43H40N10O6

Molecular Weight

792.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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