JPS014 TFA
Product Specifications
Target
PROTACs|||Apoptosis|||HDAC
Related Pathways
DNA Damage/DNA Repair|||Apoptosis|||Chromatin/Epigenetic|||PROTAC
Bioactivity
JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), particularly HDAC1/2. This activity is associated with a higher number of differentially expressed genes and increased apoptosis in HCT116 cells [1].
Molecular Formula
C48H60F3N7O9S
Molecular Weight
968.09
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6250528-01 0.1 mL
CD301 (CD301 Antigen, C-type Lectin Domain Family 10 Member A, CLEC10A, CLECSF13, C-type Lectin Superfamily Member 14, CLECSF14, HML2, Macrophage Lectin 2) (HRP)
Ask
View Details MBS6250528-02 5x 0.1 mL
CD301 (CD301 Antigen, C-type Lectin Domain Family 10 Member A, CLEC10A, CLECSF13, C-type Lectin Superfamily Member 14, CLECSF14, HML2, Macrophage Lectin 2) (HRP)
Ask
View Details 
MBS6394529-01 0.1 mL
SMURF1 (E3 Ubiquitin-protein Ligase SMURF1, hSMURF1, SMAD Ubiquitination Regulatory Factor 1, KIAA1625, SMAD-specific E3 Ubiquitin-protein Ligase 1) (MaxLight 750)
Ask
View Details MBS6394529-02 5x 0.1 mL
SMURF1 (E3 Ubiquitin-protein Ligase SMURF1, hSMURF1, SMAD Ubiquitination Regulatory Factor 1, KIAA1625, SMAD-specific E3 Ubiquitin-protein Ligase 1) (MaxLight 750)
Ask
View Details 