What is the catalog number for PF15 TFA?

The catalog number for PF15 TFA is T77932.

What sizes are available for PF15 TFA?

PF15 TFA is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does PF15 TFA come in?

PF15 TFA is available in 2 different pack sizes.

Is PF15 TFA in stock?

PF15 TFA is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PF15 TFA?

PF15 TFA is manufactured by Molfinity.

What is the estimated delivery time for PF15 TFA?

Estimated delivery time for PF15 TFA is approximately 10 business day(s), depending on your location.

PF15 TFA

Product Specifications

Target

PROTACs, FLT

Related Pathways

Tyrosine Kinase/Adaptors, PROTAC, Angiogenesis

Bioactivity

PF15 TFA, a PROTAC targeting FLT3 kinase and CRBN, exhibits selective degradation of FLT3-ITD with a DC50 of 76.7 nM. The compound potently suppresses proliferation in FLT3-ITD-positive cells, reduces phosphorylation levels of FLT3 and STAT5, and demonstrates inhibition of tumor growth in murine leukemia models [1].