BSJ-03-204 triTFA
Product Specifications
Target
PROTACs|||CDK
Related Pathways
PROTAC|||Cell Cycle/Checkpoint
Bioactivity
BSJ-03-204 triTFA is a potent and selective Cereblon- and CDK-targeted PROTAC (PROteolysis TArgeting Chimera) featuring Palbociclib-based ligands for the degradation of CDK4/6. It exhibits IC50 values of 26.9 nM for CDK4/D1 and 10.4 nM for CDK6/D1, indicating strong inhibitory capabilities. Notably, it spares IKZF1/3 from degradation and possesses anti-cancer activity [1].
Molecular Formula
C49H51F9N10O14
Molecular Weight
1174.97
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![2-{[4- (1-Pyrrolidinylcarbonyl) anilino]-carbonyl}benzoic acid](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
