Thalidomide-O-C8-COOH
Product Specifications
CAS Number
2225148-51-4
Target
Others, E3 Ligase Ligand-Linker Conjugate, Autophagy, Apoptosis
Related Pathways
PROTAC, Others, Apoptosis, Autophagy
Bioactivity
Thalidomide-O-C8-COOH, also known as Cereblon ligand 3, is a Thalidomide-derived compound that serves as a Cereblon (CRBN) ligand for the targeted recruitment of CRBN protein. It can be coupled via a linker to another ligand to create proteolysis-targeting chimeras (PROTACs) [1].
Smiles
O=C(O)CCCCCCCCOC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Molecular Formula
C22H26N2O7
Molecular Weight
430.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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