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Thalidomide-O-C8-COOH

Product Specifications

CAS Number

2225148-51-4

Target

Others|||E3 Ligase Ligand-Linker Conjugate|||Autophagy|||Apoptosis

Related Pathways

PROTAC|||Others|||Apoptosis|||Autophagy

Bioactivity

Thalidomide-O-C8-COOH, also known as Cereblon ligand 3, is a Thalidomide-derived compound that serves as a Cereblon (CRBN) ligand for the targeted recruitment of CRBN protein. It can be coupled via a linker to another ligand to create proteolysis-targeting chimeras (PROTACs) [1].

Smiles

O=C(O)CCCCCCCCOC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

Molecular Formula

C22H26N2O7

Molecular Weight

430.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Curated Selection

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