Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan
Product Specifications
CAS Number
1599439-54-9
Target
Drug-Linker Conjugates for ADC, Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is a drug-linker conjugate used in antibody-drug conjugates (ADCs), consisting of Exatecan attached via a maleimidopropyl (Mal) PEGylated tetrapeptide linker, applicable in ADC synthesis and cancer research [1].
Smiles
N(C(CCCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCOCCOCCNC(CCN2C(=O)C=CC2=O)=O)=O)=O)=O)=O)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
Molecular Formula
C57H65FN10O15
Molecular Weight
1149.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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