SN38-COOH
Product Specifications
CAS Number
2170118-23-5
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
SN38-COOH, the active metabolite of the topoisomerase I inhibitor irinotecan, is utilized in the synthesis of antibody-drug conjugates (ADCs) . It functions by inhibiting DNA and RNA synthesis [1] [2].
Smiles
O(C(CCC(O)=O)=O)[C@@]1(CC)C2=C(C(=O)N3C(=C2)C=4C(C3)=C(CC)C=5C(N4)=CC=C(O)C5)COC1=O
Molecular Formula
C26H24N2O8
Molecular Weight
492.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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