Maytansinoid B
Product Specifications
CAS Number
1628543-40-7
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Maytansinoid B, an ADC cytotoxin, conjugates with antibodies to create antibody-drug conjugates (ADCs) . This antimitotic agent binds to tubulin, inhibiting microtubule assembly, and induces G2/M arrest in the cell cycle, leading to apoptosis [1] [2].
Smiles
C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCNC)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]
Molecular Formula
C36H51ClN4O10
Molecular Weight
735.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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