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TAM558

Product Specifications

CAS Number

1802499-21-3

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

TAM558 is a payload molecule utilized in the synthesis of OMTX705, which is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470, exhibiting antitumor activity [1].

Smiles

[C@H](C[C@@H](N(C([C@@H](NC(=O)[C@@H]1N(C)CCCC1)[C@H](CC)C)=O)CCC)C(C)C)(OCCC)C2=NC(C(N[C@@H](CC3=CC=C(O)C=C3)C[C@@H](C(NNC(OCCOCCOCCOCCNC(OCC4=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN5C(=O)C=CC5=O)=O)[C@H](C)C)=O)CCCNC(N)=O)=O)C=C4)=O)=O)=O)C)=O)=CS2

Molecular Formula

C79H122N14O19S

Molecular Weight

1603.96

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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