MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan
Product Specifications
CAS Number
2414393-22-7
Target
Topoisomerase, Drug-Linker Conjugates for ADC
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Bioactivity
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is an agent-linker conjugate designed for antibody-drug conjugate (ADC) applications, comprised of an ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and the DNA topoisomerase I inhibitor, Exatecan. This conjugate is utilized in cancer research [1].
Smiles
N(C(=O)C1(OCNC(CNC([C@H](CC2=CC=CC=C2)NC(CNC(CNC(CCCCCN3C(=O)C=CC3=O)=O)=O)=O)=O)=O)CCC1)[C@@H]4C5=C6C(C=7N(C6)C(=O)C8=C(C7)[C@](CC)(O)C(=O)OC8)=NC=9C5=C(CC4)C(C)=C(F)C9
Molecular Formula
C55H60FN9O13
Molecular Weight
1074.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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