Mal-PEG8-Val-Ala-PAB-Exatecan
Product Specifications
CAS Number
2679821-39-5
Target
Topoisomerase, Drug-Linker Conjugates for ADC
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Bioactivity
Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b), an antibody-drug conjugate linker (ADC linker), binds Nectin-4 polypeptides to chemotherapeutic agents for use in cancer research [1].
Smiles
N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(=O)C=CC2=O)=O)=O)[C@@H](C)C)=O)C)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
Molecular Formula
C66H85FN8O20
Molecular Weight
1329.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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