FDW028
Product Specifications
CAS Number
2768426-49-7
Target
Akt, B7, mTOR, Autophagy, Transferase
Related Pathways
Cytoskeletal Signaling, Autophagy, Metabolism, Immunology/Inflammation, PI3K/Akt/mTOR signaling
Purity
0.9955
Bioactivity
FDW028 is a selective and potent fucosyltransferase 8 (FUT8) inhibitor with anti-tumor activity that drives B7-H3 lysosomal degradation via defucosylation and CMA pathways. FUT8 can be used to study metastatic colorectal cancer (mCRC) .
Smiles
OC1=CC(=NC2=NC(=NN21)NCC3=CC=C(C=C3)CC)CNCC=4C=CC=CC4
Molecular Formula
C22H24N6O
Molecular Weight
388.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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