KP-457
Product Specifications
CAS Number
1365803-52-6
Target
MMP
Related Pathways
Proteases/Proteasome
Purity
0.9833
Bioactivity
KP-457 is a specific inhibitor of a disintegrin-metalloproteinase 17 (ADAM17) and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF) .
Smiles
C(CS(=O)(=O)C1=CC=C(OCC#CC)C=C1)(N(C=O)O)C2=CC=C(CNS(C)(=O)=O)C=C2
Molecular Formula
C21H24N2O7S2
Molecular Weight
480.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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