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ROS-generating agent 1

Product Specifications

CAS Number

2369030-41-9

Target

Reactive Oxygen Species|||Ferroptosis|||Apoptosis|||ROS Kinase|||ROS

Related Pathways

Immunology/Inflammation|||NF-?B|||Tyrosine Kinase/Adaptors|||Apoptosis|||Metabolism

Purity

0.9976

Bioactivity

Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and ferroptosis in NCI-H460 cells.

Smiles

C(=C\1/C(=O)\C(=C\C2=CC(C(F)(F)F)=CC=C2)\CNC1)\C3=CC(C(F)(F)F)=CC=C3

Molecular Formula

C21H15F6NO

Molecular Weight

411.34

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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