YAP-TEAD-IN-3
Product Specifications
CAS Number
2714434-21-4
Target
YAP
Related Pathways
Stem Cells
Purity
0.9871
Bioactivity
YAP-TEAD-IN-3 is an inhibitor of YAP/TAZ-TEAD interactions with an IC50 of 9 nM for Avi-human TEAD (4217-434) . YAP-TEAD-IN-3 inhibits YAP reporter gene expression (IC50 = 0.048 μM) and NCI-H2052 cell proliferation (IC50 = 0.048 μM) .
Smiles
OCCOC1=C([C@@]([C@@]2=C(Cl)C(F)=CC3=C2C[C@@]([C@@H]4CCCN4)(C5=CC=CC=C5)O3)=C(C(NC)=O)C=N1)F
Molecular Formula
C27H26ClF2N3O4
Molecular Weight
529.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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