12R-LOX-IN-2
Product Specifications
CAS Number
3026677-37-9
Target
Lipoxygenase, DNA/RNA Synthesis
Related Pathways
Metabolism, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9992
Bioactivity
12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX) .12R-LOX-IN-2 inhibits imiquimod (IMQ) -induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 may be useful in the study of psoriasis and other skin-associated inflammatory diseases.
Smiles
OC=1C=CC(C2=NC=3C=CC=CC3C=C2)=C4C=CC=CC14
Molecular Formula
C19H13NO
Molecular Weight
271.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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